Research Library

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Coenzyme Q10 is necessary for our cells to function properly. It is a powerful antioxidant, naturally created inside the human body. As we age, CoQ10 levels decrease, and in some cases supplementation can help keep those levels high. CoQ10 comes in two forms, ubiquinone or ubiquinol, and is found in foods such as fish, organ meat and wheat germ. The ubiquinol form is the reduced form of CoQ10, and can immediately be used by the body.


197 pregnant women with high-risk of preeclampsia were enrolled in a randomized, double-blind, placebo-controlled trial. They were designated to receive 200mg of CoQ10 or a placebo daily from 20 weeks of pregnancy until delivery. 30 women in the placebo group experienced pre-eclampsia, compared to 17 in the CoQ10 group.

  1. Coenzyme Q10 supplementation during pregnancy reduces the risk of pre-eclampsia.

    Teran E, Hernandez I, Nieto B, Tavara R, Ocampo JE, Calle A., International journal of gynaecology and obstetrics, 2009


Patients with coronary artery disease (CAD) experience a reduction in ecSOD, an important antioxidant system within the vessel wall. 33 CAD patients were split into two groups and received 300mg of CoQ10 per day or a placebo in a 2007 study. The treatment group experienced statistically significant improvements related to their coronary artery disease: their expression of ecSOD, endothelium-dependent relaxation, and peak VO(2) and O(2) pulse increases were greater.

76 people were enrolled in a 2001 study to determine the effect of CoQ10 on blood pressure. The trial found that CoQ10 reduced systolic blood pressure better than the placebo.

  1. Effect of coenzyme Q10 administration on endothelial function and extracellular superoxide dismutase in patients with ischaemic heart disease: a double-blind, randomized controlled study.

    Tiano L, Belardinelli R, Carnevali P, Principi F, Seddaiu G, Littarru GP., European heart journal, 2007

  2. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension.

    Burke BE, Neuenschwander R, Olson RD., Souther medical journal, 2001