Research Library

This scientific research is for informational use only. The results reported may not necessarily occur in all individuals. Care/of provides this information as a service. This information should not be read to recommend or endorse any specific products.

B vitamins are found in many foods, but if you aren’t eating a balanced diet, you may be missing some of these eight essential vitamins. For instance, vitamin B12 can only be obtained through animal products. If you aren’t sure that you are getting enough B vitamins from your diet, supplementation may be beneficial to you.

Alcohol can deplete B-Vitamins

B-vitamins are very important and many people get less than the recommended daily amount of these nutrients. Frequent alcohol consumption can deplete B-vitamins, particularly Vitamin B1 (thiamin), Vitamin B6, Vitamin B12 and Folate. If alcohol is consumed, it may be beneficial to supplement with b-vitamins.

Note, the 2020-2025 Dietary Guidelines for Americans recommends that adults of legal drinking age can choose not to drink, or to drink in moderation by limiting intake to 2 drinks or less in a day for men or 1 drink or less in a day for women, on days when alcohol is consumed.

  1. Vitamins Their Role in the Human Body

    G.F.M. Ball, Blackwell Publishing Ltd., 2004

  2. Relationships between nutrition, alcohol use, and liver disease.

    Lieber CS., Alcohol Research and Health, 2003

  3. Alcohol increases homocysteine and reduces B vitamin concentration in healthy male volunteers--a randomized, crossover intervention study

    Gibson A, Q J Med, 2008

  4. Frequently asked questions - Alcohol

    Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, 2016


B vitamins are essential for the nervous system. They are important for proper and normal neurological function, chemical signaling,red blood cell formation and synthesis of DNA and RNA.

B vitamins support healthy homocysteine levels and are necessary for proper cellular functioning as they are a coenzyme for enzymatic reactions. Homocysteine plays a role in stress, with its accumulation being associated with oxidative stress, DNA strand breakage and mitochondrial membrane damage.

Many of the B vitamins are used to regulate the stress response and synthesize hormones necessary for increased physical activity, such as adrenaline and cortisol. One of the mechanisms of action by which B-vitamins support stress is through the regulation of the hormone, cortisol. Cortisol, often referred to as the ‘stress hormone’, is produced by the adrenal glands when stress is experienced as a mechanism to counteract the stress.

  1. Vitamins Their Role in the Human Body

    G.F.M. Ball, Blackwell Publishing Ltd., 2004

  2. The effect of diet components on the level of cortisol

    Stachowicz M, Lebiedzinska A., Eur Food Res Technol., 2009

  3. Nutrients and Botanicals for Treatment of Stress: Adrenal Fatigue, Neurotransmitter Imbalance, Anxiety, and Restless Sleep

    Head K, Kelly G., Alt Med Review, 2009

  4. The effects of multivitamin supplementation on diurnal cortisol secretion and perceived stress

    Camfield D, Wetherell M, Scholey A, Cox K et al, Nutrients, 2013

  5. Protective effect of folic acid on oxidative DNA damage

    Guo X, Cui H, Zhang H, Guan K et al., Medicine, 2015